De Minaur battled back from going one set down to force a decider where he held a 5-3 lead, only for Musetti to win four games in succession in an incredible round-robin match in Turin that the Italian won 7-5 3-6 7-5. At the United States Open in September De Minaur won the first set against Felix Auger-Aliassime but ended up losing his sixth Grand Slam quarterfinal.

At Wimbledon in the fourth round, he won the opening set 6-1 against Novak Djokovic only to suffer a similar fate.

–SABC–